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Studies in fly models of PD treated with NAM, NAD + , or through PARP mutations demonstrated increased NAD + levels, which also rescued mitochondrial function 283,284,285

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This asparagine residue does not allow discrimination of the extra phosphate group of NADP + (as observed in the presence of a glutamate)

Cubaa, W.J

Vor diesem Hintergrund sprechen die aktuellen Daten klar fr den Einsatz von Finerenon in Kombination mit GLP-1-Rezeptoragonisten und SGLT-2-Hemmern, um den kardio-renalen Schutz bei dieser Hochrisikopopulation zu optimieren