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We dont have equivalent high-quality data for fibromyalgia or EDS specifically, and the inflammatory profile in those conditions is different to the metabolic inflammation these studies were mostly looking at

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As the NCs are sensitive to detergents and can react with free thiols commonly present in the buffers used in sodium-dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), native PAGE was applied in these experiments

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Based on the amount of GSH in the lysate, we calculated the GSH concentration assuming an averaged HeLa/HT1080 cell volume of 4,000 m 3 (refs 15, 51, 52)

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