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For the purpose of this discussion, we will focus on substances that are commonly referred to as gateway drugs: caffeine alcohol tobacco marijuana Caffeine Image 4.2 Hot Coffee in a White Mug Surrounded by Coffee Beans on a Wood Table History and Background Caffeine is a bitter substance that occurs naturally in more than 60 plants, including coffee beans, tea leaves, kola nuts (used to flavor soft-drink colas), and cacao pods (used to make chocolate products)
The timing of initiation of e-cigarette use may be critical in the context of using these products as a smoking cessation aid because sufficient transition time is needed for some cigarette smokers to adjust to and overcome potential challenges, Xiaozhong Wen, MD, PhD, associate professor of pediatrics in the Jacobs School of Medicine and Biomedical Sciences at the State University of New York at Buffalo, and colleagues wrote
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