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Safety data from over 900 clinical trial participants demonstrates that AOD-9604 is remarkably well-tolerated with a side effect profile indistinguishable from placebo in most studies
6 Conclusion Finally, we integrate the main points from earlier sections to highlight ferroptosis as a promising research and therapeutic direction in OA (201)
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To investigate whether the increased GSH level at 100 g/ml 5-FOA (Figure S2A) was stable during longer-term cultivation of the modified strain, cellular GSH content was monitored every 10 generations during sequential batch cultivation in flasks at 100 g/ml 5-FOA (after every ~ 10 generations, aliquots of overnight culture were transferred to fresh medium giving OD 0.01 and re-incubated)
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