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Early studies focused on how it protects the gut, especially against damage from painkillers (NSAIDs) in animals

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Vascular calcification in CKD-MBD: Roles for phosphate, FGF23, and klotho

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Glutathione peroxidase 4 (GPx4), is the only enzyme in cells that can reduce lipid peroxides to normal phospholipid molecules, its activity is crucial for maintaining normal cell function and ferroptosis [74]

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Bergs V

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