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As use of GLP-1 receptor agonists continues to expand, the integration of conventional clinical evidence with large-scale observational data may offer a more complete picture of how these therapies affect patients in routine practice

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TSH at 6 to 8 weeks after starting a GLP-1 if on levothyroxine How GLP-1 Receptor Agonists Slow Gastric Emptying GLP-1 receptor agonists bind receptors in the stomach wall and vagal nerve pathways, triggering a measurable deceleration of gastric emptying