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December Dec 26: Accelerated approval doesnt always equal full clearance, something Amgen was reminded of when the FDA declined to convert Lumakras May 2021 conditional nod in KRASG12C-mutated non-small cell lung cancer (NSCLC) to a traditional one
For men, it may result in lower sperm count and motility
Gastrointestinal : lcera gstrica/duodenal experimental: contraregulacin frente a AINEs (indometacina, diclofenaco), alcohol absoluto, estrs por restriccin, isquemia-reperfusin
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