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Studies have shown that the rs822336 SNP in the PD-L1 promoter/enhancer region affects PD-L1 expression by competing for binding sites with the transcription factors C/EBP (CCAAT-enhancer-binding protein beta) and NFIC (nuclear factor I C)

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23(2): 906 Savica V, Bellinghieri G, Di Stefano C, et al