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An interesting recent study, based on complete exon sequencing, identified a surprisingly high rate of other OPRM1 variants

Choosing dipeptidyl peptidase-4 inhibitors, sodium-glucose cotransporter-2 inhibitors, or both, as add-ons to metformin: Patient baseline characteristics are crucial

Add GIP receptor activation, as Tirzepatide does, and you layer in improved insulin sensitivity, enhanced fat metabolism, and what appears to be reduced GI side effects compared to GLP-1-only approaches

When combined with a healthy diet and regular exercise, B12 injections can enhance the effectiveness of weight loss initiatives

Among women ages 50-64, that number jumps to one in five