doi:10.1056/NEJMoa1410489 Nicholls SJ, Puri R, Anderson T, et al
By activating GLP-1 receptors in the brain, semaglutide helps reduce hunger, increase feelings of fullness, and decrease food cravings
It mimics the natural GLP-1 hormone that your body releases after eating
Since 2005, there have been several glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs), including lixisenatide, exenatide, albiglutide, dulaglutide and liraglutide, recommended for the treatment of T2D approved by the US Food and Drug Administration (FDA)
Once youve lost significant weight and your body has fully adapted to your maintenance dose, the metabolic benefits of weight loss typically outweigh any medication-related tiredness