Gastrointestinal Side Effects The most frequently reported side effects of Wegovy include: Nausea: Occurring in up to 44% of participants, nausea is often most pronounced during the initial stages of treatment or when doses are increased too quickly
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2024 Meta-Analysis Indicates That GLP-1RAs Reduce Adverse CV Events GLP1-RA therapy significantly reduces the risk of major adverse cardiovascular events (MACEs), all-cause mortality, CV mortality, stroke, risk for coronary revascularization, and composite adverse kidney outcomes in both sexes, regardless of a patient's history of cardiovascular disease, BMI or eGFR (Rivera et al, 2024)
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A minimum cycle of 12 weeks is recommended, with 16-24 weeks being common for advanced users