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Final availability depends on the patients state, provider decision, pharmacy assignment and chosen treatment term

Principal coordinate analyses (PCoA) was plotted using the phyloseq package, and clustering significance was determined using the betadisper function [27] for dispersion and pairwiseAdonis.dm function [28] for orientation

Additional exclusion considerations in clinical research design: Severe renal impairment (eGFR below 30 mL/min/1.73m2)

Adults with BMI 30 kg/m, or BMI 27 with comorbidities like type 2 diabetes, hypertension, or sleep apnea, typically qualify

doi: 10.1016/S2213-8587(24)00150-5 [DOI] [PMC free article] [PubMed] [Google Scholar] 132.Papaetis GS, Kyriacou A