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Extracellular Matrix (ECM) The structural scaffold of proteins and carbohydrates surrounding cells in connective tissue

This study also identified the depletion of the purine metabolite, hypoxanthine, in chronic fatigue patients (according to Canadian Consensus criteria) which may impair ATP production and contribute to the biochemical changes associated with PEM

It is a tripeptide, meaning it is composed of three amino acids: glycine, histidine, and lysine

Feron, O., Dessy, C., Moniotte, S., Desager, J