This includes individuals with a personal or family history of medullary thyroid carcinoma, those with Multiple Endocrine Neoplasia syndrome type 2, patients with type 1 diabetes or diabetic ketoacidosis, anyone currently taking another GLP-1 receptor agonist medication, pregnant or breastfeeding individuals, and patients with active pancreatitis
In diet-induced obesity models, this inhibition has been observed to reduce white fat accumulation and promote lipolysis, effectively reprogramming metabolic pathways toward enhanced energy expenditure
Specific Carbohydrate Diet (SCD): By eliminating complex carbs, the SCD may help restore gut balance over time
The standard clinical protocol involves gradual dose escalation designed to minimize gastrointestinal side effects while building toward therapeutic levels
Vitamin B12 is also important for DNA synthesis and cell maturation