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It has the effects of invigorating spleen and nourishing liver, nourishing blood and promoting blood circulation, and softening and dispersing masses

In one early trial, no significant changes in [I]FP-CIT SPECT uptake were observed over 12 months, likely due to the advanced disease stage of participants [54]

The interaction between vascular ECs and vascular smooth muscle cells occurs directly, through main crosstalk mechanisms: paracrine regulation by bioactive molecules, communication via gap junctions, or information transfer via extracellular vesicles or extracellular matrix (ECM) [36]

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