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Additionally, pharmacologic agents such as shikonin (a PKM2 inhibitor) and dichloroacetate (a PDK1 inhibitor) have been shown to suppress TEC apoptosis and attenuate renal interstitial fibrosis (Wei et al., 2019)

Effects of menstrual cycle phase on metabolomic profiles in premenopausal women

It guides nave T cells to differentiate into regulatory T cells (Tregs), which actively suppress inflammation and stop the immune system from overreacting to harmless food antigens

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Potential renal stress markers reported in rodent studies at higher doses