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Overall Evidence for the Use of B12 for Painful Peripheral Polyneuropathy Taking into account the above evidence, there is level III evidence overall to support the use of B12 either as monotherapy or as a combination therapy for treating neuropathic pain caused by peripheral polyneuropathy

At Perfect B, symptoms are mapped to the most likely biological pathway during your consultation and your protocol is built from there

4 Unlike bioavailable forms of B12 like methylcobalamin, cyanocobalamin occurs only in trace amounts in the body, usually from cigarette smoking or other sources of cyanide

There are also concerns that pre-treating side effects can dampen your immune systems response to the antigen in the vaccine, which could make it less effective

We determine the ideal combination of B vitamins, dosage, and frequency for your specific needs and goals