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doi:10.1016/j.tins.2020.12.002

L-carnitine supplementation did not significantly affect the serum d-ROM levels after 1 month

But when you combine glucagon receptor agonism with strong GLP-1 and GIP activity, something interesting happens: GLP-1 and GIP's insulin-stimulating effects offset glucagon's glucose-raising tendency, and what's left is glucagon's other effects increased hepatic energy expenditure, upregulated fatty-acid oxidation, and thermogenesis