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The study found that L-carnitine uptake improves glycemic markers through reduction of fasting blood glucose, glycosylated hemoglobin, and HOMA-IR (homeostatic model assessment for insulin resistance) with lesser effects on insulin levels in the serum

IGF-1 Pathway Studies Preclinical research models have been used to investigate the downstream effects of GHSR-1a activation on hepatic IGF-1 expression, with evidence suggesting GHRP-2 may serve as a useful probe in studies examining GH/IGF-1 axis dynamics

Growth hormone promotes skeletal muscle cell fusion independent of insulin-like growth factor 1 up-regulation

However, as with the other health effects of Spirulina, most research is based on short-term studies involving small numbers of animals

Water Res 42:34983518