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This separation makes combining them theoretically additive, but individual responses vary based on baseline nutrient levels, liver function, and genetic predisposition to peptide sensitivity

Many adjuvants have been investigated for peptide vaccines, including particulates, oil emulsions, toll-like receptor ligands, immunostimulating complexes, and other biologically-derived materials (e.g., squalene, chitosan, alginates, and saponins) 2,3

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