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Effects of multispecies probiotic supplementation on serum bone turnover markers in postmenopausal women with osteopenia: a randomized, double-blind, placebo-controlled trial

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Exendin-4 (the glucagon-like peptide 1 receptor agonist) significantly increases SIRT1 expression, decreasing Txnip expression and XBP1s nuclear translocation through suppressing the acetylation level of H3K9 in the Txnip promoter region mediated by SIRT1, ultimately improving the renal pathological injury induced by HFD/HG

KLJ is supported by the William T