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First, it has been shown in various types of cancer such as breast, prostate, and lymphoma that iron metabolism can be reprogrammed either by the upregulation of several iron intake pathways or the downregulation of iron export and storage pathways (100, 101)

The most recent data from 2025 continues to solidify oxidative stress as the shared mechanistic basis for post-viral syndromes

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Genistein reactivates the Keap1/Nrf2 pathway, thereby increasing the levels of antioxidant proteins like heme oxygenase 1 (HO-1) and NAD(P)H quinone dehydrogenase 1, which reduce oxidative damage (Hu et al., 2021)

Li, J., Liu, J., Liu, W., Yu, X., Cao, J., An, M., & Chang, Y