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Weve explained it in detail here, but in a nutshell, stress and anxiety cause our bodies to produce more stress hormones (like cortisol) which, if produced over a prolonged period, can cause increased inflammation and tissue hypersensitivity

Brain Behav Immun 80, 889899

Furthermore, it has been reported that in comparison to normal erythrocytes, Plasmodium -infected erythrocytes produce twice as many free radicals like hydrogen peroxide (H 2 O 2 ) or hydroxyl (OH - ) [405]

Specifically, we focus on the biochemical and molecular mechanisms through which AST influences cellular processes, including oxidative stress reduction, modulation of neuroinflammation, and protection against neuronal damage