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in Nature Medicine demonstrated that blocking NNMT in white adipose tissue increased energy expenditure, reduced fat mass, and improved insulin sensitivity in animal models even without changes in diet or activity (Kraus et al., Nature Medicine )

For a 12-week protocol , estimated use increases to approximately 58.8 mg , requiring 6 vials

While such cases are rare (because thankfully, known serious injuries from BPC-157 have not come to light yet), the legal door is open