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Long-term use of semaglutide for weight loss Semaglutide, like other GLP-1 medications, is designed to be taken long-term

Aim for 7-9 hours of sleep per night and establish a consistent sleep routine to promote better sleep hygiene

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However, patients receiving pharmacologic doses of niacin (500 mg or higher) for lipid modification require closer monitoring due to niacin's known effects on insulin sensitivity and glucose homeostasis