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Transitioning off GLP-1 after 12 weeks: what to expect and how maintenance works Transitioning off GLP-1 after 12 weeks: what maintenance looks like Last updated: March 2026 Quick answer: When you transition off GLP-1 after 12 weeks, appetite cues often return gradually

doi: 10.1056/NEJMoa1614362 4 De NicolaLProvenzanoMChiodiniPD'ArrigoGTripepiGDel VecchioLet al

Andrew Kraftson, who treats obese patients at the University of Michigan, told AP that he is also encouraged by the possibility that more of his patients might be able to afford these drugs

Conclusion The GLP-1RA medication class is widely used and has growing clinical indications based on excellent clinical outcomes

You need training that is effective and realistic, not extreme