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Examples of the overall distribution of GPX1-positive cells in selected islets from several donors are depicted as assembled micrographs, where the first column shows the presence of GPX1 cells alone within islets and the surrounding regions, the second column displays merged images of cells positive for GPX1 (brown GPX1 cells converted to a blue pseudo colour), insulin (green) and glucagon (red), while the third column shows corresponding fields after counterstaining with haematoxylin (Figs

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Pituitary tumors frequently preserve responsiveness to hypophysiotropic factors, including dopamine (DA) and somatostatin (SS), ubiquitous peptides that physiologically inhibit hormone secretion and cell proliferation at both the pituitary and the periphery levels, and thus are considered as molecules with therapeutical potential ( The inhibitory actions of DA in pituitary tumors are mediated by DA receptor subtype 2 (DRD2) [reviewed in Ref