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Is IV vitamin C safe

HGF/c-Met signaling is a well-established oncogenic pathway: c-Met is amplified or overexpressed in multiple cancers (gastric, lung, renal, hepatocellular) HGF/c-Met activation promotes tumor cell proliferation, survival, invasion, and metastasis c-Met inhibitors are FDA-approved cancer drugs (cabozantinib, crizotinib, capmatinib) A compound that potentiates HGF/c-Met signaling raises theoretical concerns about promoting tumor growth or transformation with chronic use

Associations between obesity and hyperuricemia combing mendelian randomization with network pharmacology

When clofazimine was applied to infected cells for 6 h, we observed an enrichment of upregulated genes that are associated with innate-immunity-related pathways, including MAPK, interleukin and TNF responses (Extended Data Figs

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