In research models, this antagonism brings estrogen-mediated negative feedback on the hypothalamus and anterior pituitary
Axial and Appendicular Bone Mineral Density in Patients with Long-Term Deficiency or Excess of Calcitonin
GraphPad Prism 7.0 software (GraphPad Software Inc., San Diego, CA, United States) was used for the statistical analysis and data presentation
BENEFITS OF SERMORELIN: Increased muscle Increased lean body mass Decreased body fat Enhanced recovery from injuries and training session Deeper, more restful sleep Enhanced flexibility and joint health Improved overall health and wellness
Reported benefits (per available research): Studied for its ability to raise GH and IGF-1 toward youthful levels and blunt age-related loss of fat-free mass, based on a 2-year randomized, placebo-controlled trial in 65 healthy older adults (Nass et al., 2008, Annals of Internal Medicine, PMID 18981485)