16 The herbal supplements and weight-loss agents Hydroxycut and Herbalife have both been reported to cause acute liver failure, with patients presenting with either the hepatocellular or the cholestatic pattern of liver injury
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363,364 Similarly, GRP78 upregulation is detected in ALS spinal motor neurons, and region-specific UPR markers such as GRP58 and CHOP are found in prion diseases and HD, respectively
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