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Medical Writing Assistance The authors thank Manthan Mehta, Kumardeep Paul, Syed Rahman, Mansij Biswas, Arpit Jain, Jignesh Ved, from Boehringer Ingelheim (India) medical affairs for providing writing assistance for this manuscript in accordance with Good Publication Practice (GPP3) guidelines ( Authorship All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this article, take responsibility for the integrity of the work as a whole, and have given their approval for this version to be published

Safer Alternatives and Approved Treatment Pathways in the UK MHRA-authorised options for weight management include semaglutide (Wegovy, NICE TA875) and tirzepatide (Mounjaro, NICE TA1026)

HTSeqa Python framework to work with high-throughput sequencing data