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22 This inhibition reduces the local inflammatory response, creating a more conducive environment for tissue regeneration by limiting the recruitment of inflammatory cells that could otherwise contribute to tissue damage

Kontoghiorghes, G., Pattichis, K., Neocleous, K

Controlled human trials exist, but they're limited in size, focused mostly on topical cosmetic use, and usually last only a few weeks or months. That means a lot of the exciting claims, especially around gene expression, systemic repair, and anti-aging effects, haven't been confirmed in large-scale human studies

Kao et al., 2016)

With bacteriostatic water and proper refrigerator storage, most researchers use reconstituted retatrutide within 2-4 weeks