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5 Hypoxic stress at high altitude can trigger a series of physiological responses across multiple organ systems, especially the brain (increased cerebral blood flow), pulmonary system (increased ventilation and pulmonary vascular remodeling), cardiovascular system (increased heart rate, cardiac output, and systemic blood pressure), renal system (increased bicarbonate excretion and erythropoietin (EPO) secretion), and hematologic system (increased red cell mass, hemoglobin (Hb) concentration, and hematocrit (Hct)), thereby increasing oxygen content and delivery in the body

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2.3 Polyphenols with translational relevance A large number of polyphenols have been investigated for PsO

Two key enzymes, ADH (alcohol dehydrogenase) and ALDH (aldehyde dehydrogenase), are responsible for metabolizing alcohol, by helping to break down alcohol molecules into smaller parts that can then be eliminated

Always consult your healthcare provider before choosing the right option for your needs