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Prooxidative effect of riboflavin Although riboflavin has been widely examined as an antioxidant in experimental studies, it can also have a prooxidant effect when exposed to ultraviolet irradiation

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Fireground Specific Nutrition Practices: Pre/Post Exposure Pre-Incident Hydrate before and during shift Maintain good electrolyte balance Consume antioxidant rich foods Avoid ultra-processed foods that can add xenobiotic burden Support gut integrity - avoid going on shift fasted Post-Incident Firefighters experience a toxic window post-fire when skin absorption is elevated due to heat, sweat, and vasodilation Strategic post-incident recovery can support detox efficiency: Immediate rehydration + electrolytes Protein to support glutathione and tissue repair Fruits/vegetables for antioxidant support Soluble and insoluble fiber to enhance GI elimination Avoid alcohol for ~24 hours as it impairs detox enzymes Non-Nutritional Strategies to Reduce Toxic Load 1

On U100 syringes, 1 unit is 0.01 mL, so mg must be translated through concentration

McGown recommends the following: Start at the lowest dose and then increase slowly based on the manufacturers recommendations