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Using the data from 19 case-controlled studies, 5 cross-sectional studies, and 3 prospective studies published before 1995, the meta-analysis of Boushey and colleagues (Boushey et al, 1995) relating basal hyperhomocysteinemia to atherosclerotic vascular disease indicates that, above 10 mol/L, a 5 mol/L increment in circulating homocysteine is associated with a significant increase in the risk of coronary artery disease (60% in men and 80% in women)
Thats a real thing, and its caused by hydrogen peroxide not applied from the outside, but produced from within
However, the mechanisms in humans are still being studied, and larger randomized trials are needed to figure out how generalizable these effects are
Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, et al
