Resmetirom (Rezdiffra TM ), a liver-directed thyroid hormone receptor- (THR-) agonist, received accelerated FDA approval in March 2024 as the first agent specifically indicated for non-cirrhotic MASH with moderate-to-advanced fibrosis (F2-F3), based on the MAESTRO-NASH trial demonstrating MASH resolution and fibrosis improvement
Liver Sauce phytonutrients and bitters support liver function
Synthetic antioxidants provide targeted support, while natural oxidants, derived from plant sources, contribute to a holistic and sustainable therapeutic strategy since they are used within regulations parameters (197)
Lo Sasso, G
Administration of NatuREN G, an innovative synbiotics mixture comprising Bifidobacterium animalis , BLC1 (10 9 cells), Lacticaseibacillus casei , LC4P1 (10 9 cells), fructooligosaccharides (2.5 g), inulin (2.5 g), quercetin (640 mg), resveratrol (230 mg), and proanthocyanidins (13 mg) to stages IIIb-IV CKD patients for 3 months reveal an increase in the ratio of Firmicutes/Bacteriodetes in the synbiotic group (Celano et al., 2023)