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Semaglutide is a prescription medication that has gained attention in recent years for its role in managing diabetes and helping with weight loss

Research shows that most patients regain a significant portion of lost weight after discontinuing semaglutide if lifestyle changes are not maintained

PMID: 41812831 ACS Appl Mater Interfaces 2026 Jun 10;18(22):31046-31060

Nevertheless, healthcare providers should consider these factors when prescribing semaglutide, especially for patients with a history of gallbladder disease or other risk factors for gallstone formation

Patients typically lose two to four pounds per month during this window, with cumulative loss reaching ten to twenty pounds by week sixteen